The Pharmacokinetics of Doxycycline in Channel Catfish (Ictalurus punctatus) Following Intravenous and Oral Administrations
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چکیده
منابع مشابه
Channel Catfish Ictalurus punctatus
We used a two-compartment, clearance volume-based model to examine rubidium and cesium Ž . pharmacokinetics in channel catfish Ictalurus punctatus after intravascular administration. We compared the apparent volumes of distribution in the central and peripheral compartments and the intercompartmental and whole-body clearances of both metals at 20.0 8C and 27.5 8C. Biological half-times of Rb we...
متن کاملFlorfenicol pharmacokinetics following intravenous and oral administrations and its elimination after oral and bath administrations in common carp (Cyprinus carpio)
The aim of this study was to evaluate pharmacokinetic profiles of florfenicol after a single dose of intravenous (5.00 mg kg-1 body weight) and oral (40.00 mg kg-1 body weight) administrations in common carp (Cyprinus carpio). The residue depletion of florfenicol was also investigated after oral administration (10.00 mg kg-1 body weight) and bath treatm...
متن کاملPharmacokinetics, tissue distribution, and metabolism of flumequine in channel catfish ž / Ictalurus punctatus
Ž . The pharmacokinetics and metabolism of the fluoroquinolone drug flumequine FLU were Ž . Ž . examined after intravascular 1 mgrkg or oral 5 mgrkg dosing in channel catfish. Parent FLU concentrations in plasma declined slowly after intravascular dosing, with a half-life of 25 h. After Ž . oral dosing, FLU concentrations in plasma were highest 3.1 mgrml at 14 h after dosing; absorption and eli...
متن کاملHigh-quality genome assembly of channel catfish, Ictalurus punctatus
BACKGROUND The channel catfish (Ictalurus punctatus), a species native to North America, is one of the most important commercial freshwater fish in the world, especially in the United States' aquaculture industry. Since its introduction into China in 1984, both cultivation area and yield of this species have been dramatically increased such that China is now the leading producer of channel catf...
متن کاملEstimating the Oral Bioavailability of Methylmercury to Channel Catfish (ictalurus Punctatus)
In classical pharmacology, oral bioavailability of a toxicant is defined as that fraction of an orally administered dose reaching the systemic circulation of the animal. The present study estimates the bioavailability of methylmercury in channel catfish (Ictalurus punctatus) by comparing concentrations in the blood through time after oral and intra-arterial (IA) administration. Catfish were can...
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ژورنال
عنوان ژورنال: Frontiers in Veterinary Science
سال: 2020
ISSN: 2297-1769
DOI: 10.3389/fvets.2020.577234